[Drug of the month. Varenicline (Champix)]
[Article in
French]
Affiliations
- PMID: 17461303
Item in Clipboard
[Drug of the month. Varenicline (Champix)]
[Article in
French]
Rev Med Liege.
2007 Feb.
Free article
Abstract
Smoking is responsible for 20,000 premature deaths per year in Belgium. Paradoxically, few drugs are efficient to induce tobacco cessation and to decrease relapse. Until a few weeks ago nicotin replacement therapy and bupropion only were validated in this indication. Varenicline (Champix), a partial agonist of nicotinic receptors, is a novel type of drugs currently also accepted for sale for smoking cessation. This article dwells on recent publications about efficacy of varenicline. Position, side-effects and advantages of the drug are discussed.
Similar articles
-
Varenicline for smoking cessation: definite promise, but no panacea.JAMA. 2006 Jul 5;296(1):94-5. doi: 10.1001/jama.296.1.94. JAMA. 2006. PMID: 16820552 No abstract available.
-
Smoking cessation with varenicline, a selective alpha4beta2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up.Arch Intern Med. 2006 Aug 14-28;166(15):1561-8. doi: 10.1001/archinte.166.15.1561. Arch Intern Med. 2006. PMID: 16908788 Clinical Trial.
-
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial.JAMA. 2006 Jul 5;296(1):56-63. doi: 10.1001/jama.296.1.56. JAMA. 2006. PMID: 16820547 Clinical Trial.
-
Which is the best primary medication for long-term smoking cessation--nicotine replacement therapy, bupropion or varenicline?Expert Opin Pharmacother. 2007 Dec;8(17):2903-15. doi: 10.1517/14656566.8.17.2903. Expert Opin Pharmacother. 2007. PMID: 18001252 Review.
-
Non-nicotinic therapies for smoking cessation.Annu Rev Pharmacol Toxicol. 2007;47:541-64. doi: 10.1146/annurev.pharmtox.47.120505.105354. Annu Rev Pharmacol Toxicol. 2007. PMID: 17209799 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
