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Review
. 2007 Sep;8(3):185-98.
doi: 10.1007/s11154-007-9035-3.

Molecular profiling in breast cancer

Shannon R Morris  1 , Lisa A Carey
Affiliations
Review

Molecular profiling in breast cancer

Shannon R Morris et al. Rev Endocr Metab Disord. 2007 Sep.

Abstract

Molecular profiling has provided biological evidence for the heterogeneity of breast cancer through the identification of intrinsic subtypes like Luminal A, Luminal B, HER2+/ER- and basal-like. It has also led to the development of clinically applicable gene expression-based prognostic panels like the Mammaprint and Oncotype Dx. The increasingly sophisticated understanding allowed by this and similar technology promises future individualized therapy.

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