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Clinical Trial
. 2007 Apr;106(4 Suppl):282-7.
doi: 10.3171/ped.2007.106.4.282.

Predicting functional change from preintervention measures in selective dorsal rhizotomy

Jack R Engsberg  1 , Sandy A Ross, David R Collins, Tae Sung Park
Affiliations
Clinical Trial

Predicting functional change from preintervention measures in selective dorsal rhizotomy

Jack R Engsberg et al. J Neurosurg. 2007 Apr.

Abstract

Object: In this investigation the authors attempted to predict change in function following selective dorsal rhizotomy (SDR) and intensive physical therapy in patients with spastic diplegic cerebral palsy (CP) based on multidomain preintervention measures.

Methods: Data pertaining to 22 children with CP were collected before the SDR and again 20 months afterward. Although equations for predicting change in gait speed and function (such as the Gross Motor Function Measure) were derived, the 95% confidence interval (CI) widths were too broad to make accurate predictions that were clinically useful outside the study group.

Conclusions: Future work should be focused on developing additional measures such as lower-extremity motor control and balance in an attempt to reduce the CIs to more clinically relevant values.

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Figures

Fig. 1
Fig. 1
Graph showing the 95% CI widths from the regression analysis and explained variances for within- and outside (novel)–group predictions for change in gait speed. s = second.
Fig. 2
Fig. 2
Graph showing the 95% CI widths from the regression analysis and explained variances for within- and outside (novel)–group predictions for change in GMAE.
See this image and copyright information in PMC

References

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