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. 1977 Jun;39(6):2508-12.
doi: 10.1002/1097-0142(197706)39:6<2508::aid-cncr2820390630>3.0.co;2-x.

Isolation and characterization of a neuroblastoma cell line from peripheral blood in a patient with disseminated disease

J M Gerson, H R Schlesinger, P Sereni, P S Moorhead, K Hummeler

Isolation and characterization of a neuroblastoma cell line from peripheral blood in a patient with disseminated disease

J M Gerson et al. Cancer. 1977 Jun.

Abstract

Circulation in the blood stream of neuroblastoma cells was confirmed by establishment of a cell line from the peripheral blood of a child with disseminated disease. The morphologic, enzymatic, and chromosomal pattern of this cell line was similar to a cell line established from the primary tumor on a previous occasion. The peripheral blood smear did not demonstrate tumor cells but increased numbers of atypical monocytes; lymphoblasts were evident, which may have been unrecognized neuroblasts.

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