Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2007 May 1;104(18):7317-8.
doi: 10.1073/pnas.0702503104. Epub 2007 Apr 27.

To sleep, perchance to integrate

Howard Eichenbaum  1
Affiliations
Comment

To sleep, perchance to integrate

Howard Eichenbaum. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
The effect of sleep on the organization of memory representations suggested by the findings of Ellenbogen et al. (4). Immediately after learning, the representation of each premise is constituted as the choice of one item over another (A>B, etc.), and these premises are isolated from one another despite having overlapping elements. After a 12-h period with no sleep, the premise representations are partially integrated by their overlapping elements, sufficient to support first-order transitive inferences. If the subjects sleep during the 12-h period, then the premise representations are fully interleaved, supporting both first- and second-order transitive inferences.
See this image and copyright information in PMC

Comment on

  • Human relational memory requires time and sleep.
    Ellenbogen JM, Hu PT, Payne JD, Titone D, Walker MP. Ellenbogen JM, et al. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7723-8. doi: 10.1073/pnas.0700094104. Epub 2007 Apr 20. Proc Natl Acad Sci U S A. 2007. PMID: 17449637 Free PMC article.

References

    1. Siegel JM. Science. 2001;294:1058–1063. - PMC - PubMed
    1. Vertes RP. Neuron. 2004;44:135–148. - PubMed
    1. Ellenbogen JM, Payne JD, Stickgold R. Curr Opin Neurobiol. 2006;16:716–722. - PubMed
    1. Ellenbogen JM, Hu PT, Payne JD, Titone D, Walker MP. Proc Natl Acad Sci USA. 2007;104:7723–7728. - PMC - PubMed
    1. Wilson MA, McNaughton BL. Science. 1994;265:676–679. - PubMed