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Review
. 2007 May 1;17(9):R324-6.
doi: 10.1016/j.cub.2007.03.011.

Genome integrity: a HAT needs a chaperone

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Free article
Review

Genome integrity: a HAT needs a chaperone

Craig L Peterson. Curr Biol. .
Free article

Abstract

Histone acetylation helps to maintain integrity of the yeast replisome in response to genotoxic agents. Four groups have now identified protein Rtt109p as the catalytic subunit of a novel histone H3 acetylase complex that harbors a histone chaperone subunit essential for significant activity.

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