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Case Reports
. 2007 Feb;13(2):315-7.
doi: 10.3201/eid1302.060747.

Ertapenem resistance of Escherichia coli

Marie-Frédérique Lartigue  1 , Laurent Poirel, Claire Poyart, Hélène Réglier-Poupet, Patrice Nordmann
Affiliations
Case Reports

Ertapenem resistance of Escherichia coli

Marie-Frédérique Lartigue et al. Emerg Infect Dis. 2007 Feb.

Abstract

An ertapenem-resistant Escherichia coli isolate was recovered from peritoneal fluid in a patient who had been treated with imipenem/cilastatin for 10 days. Ertapenem resistance may be explained by a defect in the outer membrane protein and production of extended-spectrum beta-lactamase CTX-M-2.

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Figures

Figure
Figure
Outer membrane protein (OMP) profiles of Escherichia coli strains. OMP content was determined by using sodium dodecyl sulfate–polyacrylamide gel electrophoresis. Lane 1 corresponds to E. coli CO clinical isolate; lane 2, E. coli JF 568 strain expressing OmpC; lane 3, E. coli JF 701 strain lacking OmpC (9). The molecular mass marker (M) and corresponding sizes (in kilodaltons) are indicated on the left. Horizontal arrows on the right indicate positions of the OMPs OmpF, OmpC, and OmpA.
See this image and copyright information in PMC

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