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Comment
. 2007 May 4;129(3):453-4.
doi: 10.1016/j.cell.2007.04.023.

Vitamins and aging: pathways to NAD+ synthesis

John M Denu  1
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Free article
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Vitamins and aging: pathways to NAD+ synthesis

John M Denu. Cell. .
Free article

Abstract

Recent genetic evidence reveals additional salvage pathways for NAD(+) synthesis. In this issue, Belenky et al. (2007) report that nicotinamide riboside, a new NAD(+) precursor, regulates Sir2 deacetylase activity and life span in yeast. The ability of nicotinamide riboside to enhance life span does not depend on calorie restriction.

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