Comment
doi: 10.1016/j.cell.2007.04.021.
BDNF instructs the kinase LKB1 to grow an axon
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- PMID: 17482540
- DOI: 10.1016/j.cell.2007.04.021
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Comment
BDNF instructs the kinase LKB1 to grow an axon
Cell.
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Abstract
Determining which neurite of a differentiating neuron is to become the axon is a crucial step in neuronal morphogenesis. Two groups (Barnes et al., 2007; Shelly et al., 2007) now report that axon specification in vivo is mediated by extracellular signals acting through the serine/threonine kinase LKB1.
Comment on
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LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.Cell. 2007 May 4;129(3):549-63. doi: 10.1016/j.cell.2007.03.025. Cell. 2007. PMID: 17482548
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LKB1/STRAD promotes axon initiation during neuronal polarization.Cell. 2007 May 4;129(3):565-77. doi: 10.1016/j.cell.2007.04.012. Cell. 2007. PMID: 17482549
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