Consecutive pregnancies in a menopausal woman following oocyte donation

Abstract

A second pregnancy was successfully achieved by a menopausal women who had previously conceived and delivered an infant using donated oocytes. The same nonanonymous oocyte donor provided the gametes for both procedures. Prior to embryo transfer, the functionally agonadal recipient received exogenous steroid hormone replacement therapy. Both pregnancies followed the transfer of 5 embryos which were conceived by the in vitro fertilization of the donated oocytes with the recipient husband's sperm. The first pregnancy ended with an intrauterine fetal demise at 40 weeks gestation. The second pregnancy is proceeding unremarkably.