doi: 10.3324/haematol.10923.
ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?
- PMID: 17488701
- DOI: 10.3324/haematol.10923
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ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?
Haematologica.
2007 May.
Free article
Abstract
In this study we investigated the relevance of the oncogenic protein NPM-ALK in regulating cellular pH (pHi) through the modulation of Na+/H+ exchanger 1 (NHE1)-activity and the consequences of pHi pharmacological manipulation in cells expressing NPM-ALK.
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