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. 2007 May;92(5):706-7.
doi: 10.3324/haematol.10923.

ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?

Francesco Turturro, Michael Driscoll, Ellen Friday, Tomas Welbourne
Free article

ALK-mediated Na+/H+ exchanger-dependent intracellular alkalinization: does it matter for oncogenesis?

Francesco Turturro et al. Haematologica. 2007 May.
Free article

Abstract

In this study we investigated the relevance of the oncogenic protein NPM-ALK in regulating cellular pH (pHi) through the modulation of Na+/H+ exchanger 1 (NHE1)-activity and the consequences of pHi pharmacological manipulation in cells expressing NPM-ALK.

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