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Comment
. 2005 Winter;2(4):187-9; discussion 190-1.
doi: 10.1900/RDS.2005.2.187. Epub 2006 Feb 10.

Limitations in immunotherapy with CD3 antibodies: comment on the article by Drs. Chatenoud and Bach

Damien Bresson  1 , Matthias von Herrath
Affiliations
Comment

Limitations in immunotherapy with CD3 antibodies: comment on the article by Drs. Chatenoud and Bach

Damien Bresson et al. Rev Diabet Stud. 2005 Winter.
No abstract available

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Comment on

References

    1. Chatenoud L, Bach JF. Questioning four preconceived ideas on immunotherapy of clinical type 1 diabetes: lessons from recent CD3 antibody trials. Rev Diabetic Stud. 2005;2(3):116–120. - PMC - PubMed
    1. Herold KC, Hagopian W, Auger JA, Poumian-Ruiz E, Taylor L, Donaldson D, Gitelman SE, Harlan DM, Xu D, Zivin RA, Bluestone JA. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med. 2002;346(22):1692–1698. - PubMed
    1. Keymeulen B, Vandemeulebroucke E, Ziegler AG, Mathieu C, Kaufman L, Hale G, Gorus F, Goldman M, Walter M, Candon S et al. Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med. 2005;352(25):2598–2608. - PubMed
    1. Herold KC, Gitelman SE, Masharani U, Hagopian W, Bisikirska B, Donaldson D, Rother K, Diamond B, Harlan DM, Bluestone JA. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes. 2005;54(6):1763–1769. - PMC - PubMed
    1. Hirsch R, Gress RE, Pluznik DH, Eckhaus M, Bluestone JA. Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells. J Immunol. 1989;142(3):737–743. - PubMed

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