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Review
. 2007 Jun;20(6):481-9.
doi: 10.1111/j.1432-2277.2006.00448.x.

The role of complement and Toll-like receptors in organ transplantation

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Free article
Review

The role of complement and Toll-like receptors in organ transplantation

Tao Lin et al. Transpl Int. 2007 Jun.
Free article

Abstract

The innate immune system not only participates in host defence but also contributes to the control of adaptive immune responses. Complement and Toll-like receptors (TLR) are key components of innate immunity. Emerging evidence suggests their activation is involved in all major aspects of transplantation. This paper reviews the current understanding of how the complement and TLR on impact transplant injury.

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