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. 2007 Jan;17(1):57-62.
doi: 10.1111/j.1750-3639.2007.00056.x.

Alois Alzheimer: his life and times

Michel Goedert  1 , Bernardino Ghetti
Affiliations

Alois Alzheimer: his life and times

Michel Goedert et al. Brain Pathol. 2007 Jan.

Abstract

Between national unification and World War I, Germany was preeminent in many areas of science and medicine. Alois Alzheimer, who lived during this period, was one of the founders of the field of neuropathology. His name will always be linked with the form of dementia that he described 100 years ago. Here we mark this anniversary by discussing Alzheimer's contributions to dementia research in the context of his life and times.

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Figures

Figure 1
Figure 1
Alois Alzheimer (1864–1915).
Figure 2
Figure 2
Franz Nissl (1860–1919).
Figure 3
Figure 3
Emil Kraepelin (1856–1926).
Figure 4
Figure 4
Max Bielschowsky (1869–1940).
Figure 5
Figure 5
The abnormal deposits that Alzheimer described. A. Neurofibrillary tangles (brown) and neuritic plaques (dark blue) in Alzheimer’s disease. Tangles were stained with an antibody against tau protein and plaques with an antibody against β‐amyloid. B. Pick bodies (brown) in Pick’s disease. They were stained with an antibody against tau protein.
See this image and copyright information in PMC

References

    1. Alzheimer A (1891) Über einen Fall von spinaler progressiver Muskelatrophie mit hinzutretender Erkrankung bulbärer Kerne und der Rinde. Arch Psychiat Nervenkrankh 23:459–485.
    1. Alzheimer A (1894) Die arteriosklerotische Atrophie des Gehirns. Neurol Centralbl 13:765–767.
    1. Alzheimer A (1896) Die Frühform der allgemeinen progressiven Paralyse. Allg Z Psychiat 52:533–595.
    1. Alzheimer A (1896) Ein “geborener Verbrecher”. Arch Psychiat Nervenkrankh 28:327–353.
    1. Alzheimer A (1904) Histologische Studien zur Differentialdiagnose der progressiven Paralyse. In: Histologische und histopathologische Arbeiten. Nissl F, Alzheimer A (eds), 1, pp. 1–297. Fischer Verlag: Jena.

Personal name as subject