[Study of the mitotic activity during the preneoplastic period in the liver of rats treated by diethylnitrosamine (author's transl)]
- PMID: 174933
- DOI: 10.1007/BF01932649
[Study of the mitotic activity during the preneoplastic period in the liver of rats treated by diethylnitrosamine (author's transl)]
Abstract
The chronic administration of diethylnitrosamine in drinking water induces liver tumors in the rat. The preneoplastic period may be divided in two phases differing mainly in the loss of circadian control of mitotic activity in hepatocytes.
Similar articles
-
Variations of liver cell control during diethylnitrosamine carcinogenesis.Eur J Cancer (1965). 1977 Jan;13(1):13-8. doi: 10.1016/0014-2964(77)90223-7. Eur J Cancer (1965). 1977. PMID: 139311 No abstract available.
-
Quantitative study on foci of altered liver cells induced in the rat by a single dose of diethylnitrosamine and partial hepatectomy.J Natl Cancer Inst. 1972 Jul;49(1):93-106. J Natl Cancer Inst. 1972. PMID: 4114003 No abstract available.
-
Influence of a chronic administration of diethylnitrosamine on the relation between specific tissular and division functions in the rat liver.Eur J Cancer (1965). 1975 Aug;11(8):531-6. doi: 10.1016/0014-2964(75)90124-3. Eur J Cancer (1965). 1975. PMID: 1222760 No abstract available.
-
Isolation and culture of adult rat hepatocytes and preneoplastic nodules from diethylnitrosamine treated livers: glucose-6-phosphatase distribution, albumin synthesis and hepatic binding protein activity.Ann N Y Acad Sci. 1980;349:413-5. doi: 10.1111/j.1749-6632.1980.tb29555.x. Ann N Y Acad Sci. 1980. PMID: 6261638 No abstract available.
-
[Early histochemical markers of hepatocarcinogenesis].Eksp Onkol. 1984;6(1):11-6. Eksp Onkol. 1984. PMID: 6209085 Review. Russian.
Cited by
-
Promotion mechanism of phenobarbital and partial hepatectomy in DENA hepatocarcinogenesis cell kinetics effect.Br J Cancer. 1983 Apr;47(4):517-25. doi: 10.1038/bjc.1983.82. Br J Cancer. 1983. PMID: 6849796 Free PMC article.
-
Effects of discontinuation of chronic feeding of diethylnitrosamine on the development of hepatomas in adult rats.Br J Cancer. 1979 Aug;40(2):260-7. doi: 10.1038/bjc.1979.174. Br J Cancer. 1979. PMID: 475971 Free PMC article.