Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1991 May;15(2):57-64.
doi: 10.1007/BF00364840.

The role of glycation in aging and diabetes mellitus

M A van Boekel  1
Affiliations
Review

The role of glycation in aging and diabetes mellitus

M A van Boekel. Mol Biol Rep. 1991 May.

Abstract

One of the hypotheses trying to explain the process of aging is the idea of glycation of proteins. This reaction, also called the Maillard or browning reaction, may explain age-related symptoms such as cataract, atherosclerosis and modification of collagen-containing tissues. Diabetics, which possess elevated blood sugar levels, show signs of accelerated aging exposing similar complications. The Maillard reaction, which occurs on a large scale in vivo, may play a key role in the initiation of these symptoms.

PubMed Disclaimer

References

    1. Diabetes. 1984 Feb;33(2):130-4 - PubMed
    1. Ann Intern Med. 1984 Oct;101(4):527-37 - PubMed
    1. J Lab Clin Med. 1962 Aug;60:302-19 - PubMed
    1. Diabetes. 1986 Aug;35(8):916-21 - PubMed
    1. Biochem J. 1987 Sep 15;246(3):761-9 - PubMed

LinkOut - more resources