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. 2007 Jul 15;23(14):1866-7.
doi: 10.1093/bioinformatics/btm255. Epub 2007 May 12.

DoriC: a database of oriC regions in bacterial genomes

Feng Gao  1 , Chun-Ting Zhang
Affiliations

DoriC: a database of oriC regions in bacterial genomes

Feng Gao et al. Bioinformatics. .

Abstract

Replication origins (oriCs) of bacterial genomes currently available in GenBank have been predicted by using a systematic method comprising the Z-curve analysis for nucleotide distribution asymmetry, DnaA box distribution, genes adjacent to candidate oriCs and phylogenetic relationships. These oriCs are organized into a MySQL database, DoriC, which provides extensive information and graphical views of the oriC regions. In addition, users can Blast a query sequence or even a whole genome against DoriC to find a homologous one. DoriC will be updated timely and the latest version is DoriC 1.8, in which oriCs of 425 genomes (468 chromosomes) are identified.

Availability: DoriC can be accessed from http://tubic.tju.edu.cn/doric/.

Supplementary information: Supplementary data are available at http://tubic.tju.edu.cn/doric/supplementary.htm.

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