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. 2007 Jun;40(9-10):749-50.
doi: 10.1016/j.clinbiochem.2007.04.002. Epub 2007 Apr 19.

Percentage non-caeruloplasmin bound copper

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Percentage non-caeruloplasmin bound copper

Patrick J Twomey et al. Clin Biochem. 2007 Jun.

Abstract

Objectives: To compare percentage non-caeruloplasmin bound copper (%NCC) to generally accepted values.

Design and methods: Using data for 338 normal individual patients, we calculated the %NCC.

Results: The %NCC ranged (median) from -59.75% to 51.98% (8.75%) respectively. The non-parametric reference interval was -23.44% to 22.99% with 43.8% of the %NCC values >10%.

Conclusions: We found the %NCC to be higher than generally accepted. This may be due to uncertainty from precision, bias and specificity.

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