Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007;36 Suppl 2(Suppl 2):T54-60.
doi: 10.1016/j.neuroimage.2007.03.018. Epub 2007 Mar 27.

fMRI studies of eye movement control: investigating the interaction of cognitive and sensorimotor brain systems

John A Sweeney  1 , Beatriz Luna, Sarah K Keedy, Jennifer E McDowell, Brett A Clementz
Affiliations
Review

fMRI studies of eye movement control: investigating the interaction of cognitive and sensorimotor brain systems

John A Sweeney et al. Neuroimage. 2007.

Abstract

Functional neuroimaging studies of eye movement control have been a useful approach for investigating the interaction of cognitive and sensorimotor brain systems. Building on unit recording studies of behaving nonhuman primates and clinical studies of patients with a focal brain lesion, functional neuroimaging studies have elucidated a pattern of hierarchical organization through which prefrontal and premotor systems interact with sensorimotor systems to support context-dependent adaptive behavior. Studies of antisaccades, memory-guided saccades, and predictive saccades have helped clarify how cognitive brain systems support contextually guided and internally generated action. The use of cognitive and sensorimotor eye movement paradigms is being used to develop a better understanding of life span changes in neurocognitive systems from childhood to late life, and about behavioral and systems-level brain abnormalities in neuropsychiatric disorders.

PubMed Disclaimer

References

    1. Berman RA, Colby CL. Spatial working memory in human extrastriate cortex. Physiol Behav. 2002;77:621–627. - PubMed
    1. Berman RA, Colby CL, Genovese CR, Voyvodic JT, Luna B, Thulborn KR, Sweeney JA. Cortical networks subserving pursuit and saccadic eye movements in humans: an fMRI study. Hum Brain Mapp. 1999;8:209–225. - PMC - PubMed
    1. Bruce CJ, Goldberg ME. Primate frontal eye fields. I Single neurons discharging before saccades. J Neurophysiol. 1985;53:603–635. - PubMed
    1. Bunge SA. How we use rules to select actions: a review of evidence from cognitive neuroscience. Cogn Affect Behav Neurosci. 2004;4:564–579. - PubMed
    1. Bunge SA, Dudukovic NM, Thomason ME, Vaidya CJ, Gabrieli JD. Immature frontal lobe contributions to cognitive control in children: evidence from fMRI. Neuron. 2002;33:301–311. - PMC - PubMed