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. 2007 Jul;178(1):74-8; discussion 78.
doi: 10.1016/j.juro.2007.03.022. Epub 2007 May 11.

Urachal carcinoma: contemporary surgical outcomes

Harry W Herr  1 , Bernard H Bochner, David Sharp, Guido Dalbagni, Victor E Reuter
Affiliations

Urachal carcinoma: contemporary surgical outcomes

Harry W Herr et al. J Urol. 2007 Jul.

Abstract

Purpose: We determined surgical outcomes in a contemporary series of patients who underwent surgery for urachal carcinoma.

Materials and methods: A cohort of 50 patients with clinically staged localized urachal carcinoma underwent extended partial cystectomy, including the urachal tumor mass and entire urachus. The patients were followed a median of 5+ years for cancer-free survival.

Results: Of the 50 patients 93% (26 of 28) with tumor confined to the urachus and bladder survived compared to 69% (9 of 13) with extravesical or peri-urachal tumor invasion and none (9 patients) with tumor invasion into the peritoneal cavity. Local recurrence was noted in 9 patients (18%) and 2 had salvage therapy. The most significant predictors of survival were pathological tumor stage and negative surgical margins.

Conclusions: Wide resection of the tumor mass and entire urachus resulting in negative soft tissue and bladder margins cures the majority of nonmetastatic urachal cancers.

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