Current concepts in normal and defective angiogenesis: implications for systemic sclerosis
- PMID: 17502049
- DOI: 10.1007/s11926-007-0013-2
Current concepts in normal and defective angiogenesis: implications for systemic sclerosis
Abstract
Vascular abnormalities are a major component of systemic sclerosis, but little is known about the events or mechanisms that initiate vascular injury and prevent its repair. Early stages of systemic sclerosis are characterized by an exaggerated angiogenic response later replaced by defective wound healing and fibrosis. In this review, we summarize the current knowledge of the angiogenic imbalance in systemic sclerosis.
Similar articles
-
Vascular disease in scleroderma: angiogenesis and vascular repair.Rheum Dis Clin North Am. 2008 Feb;34(1):73-9; vi. doi: 10.1016/j.rdc.2007.12.006. Rheum Dis Clin North Am. 2008. PMID: 18329533 Review.
-
Proangiogenic hematopoietic cells of monocytic origin: roles in vascular regeneration and pathogenic processes of systemic sclerosis.Histol Histopathol. 2013 Feb;28(2):175-83. doi: 10.14670/HH-28.175. Histol Histopathol. 2013. PMID: 23275301 Review.
-
Angiogenesis Dysregulation in the Pathogenesis of Systemic Sclerosis.Biomed Res Int. 2017;2017:5345673. doi: 10.1155/2017/5345673. Epub 2017 Jul 16. Biomed Res Int. 2017. PMID: 28791304 Free PMC article. Review.
-
Defective vasculogenesis in systemic sclerosis.Lancet. 2004 Aug 14-20;364(9434):603-10. doi: 10.1016/S0140-6736(04)16853-0. Lancet. 2004. PMID: 15313361
-
Angiogenesis and vasculopathy in systemic sclerosis: evolving concepts.Curr Rheumatol Rep. 2012 Feb;14(1):56-63. doi: 10.1007/s11926-011-0219-1. Curr Rheumatol Rep. 2012. PMID: 22083296 Review.
Cited by
-
In vivo angiogenesis screening and mechanism of action of novel tanshinone derivatives produced by one-pot combinatorial modification of natural tanshinone mixture from Salvia miltiorrhiza.PLoS One. 2014 Jul 3;9(7):e100416. doi: 10.1371/journal.pone.0100416. eCollection 2014. PLoS One. 2014. PMID: 24992590 Free PMC article.
-
Abnormalities in the regulators of angiogenesis in patients with scleroderma.J Rheumatol. 2009 Mar;36(3):576-82. doi: 10.3899/jrheum.080516. Epub 2009 Feb 17. J Rheumatol. 2009. PMID: 19228661 Free PMC article.
-
Neurological, cardiac, musculoskeletal, and renal manifestations of scleroderma along with insights into its genetics, pathophysiology, diagnostic, and therapeutic updates.Health Sci Rep. 2024 Apr 24;7(4):e2072. doi: 10.1002/hsr2.2072. eCollection 2024 Apr. Health Sci Rep. 2024. PMID: 38660003 Free PMC article.
-
Microvascular involvement in systemic sclerosis and systemic lupus erythematosus.Microcirculation. 2019 Apr;26(3):e12440. doi: 10.1111/micc.12440. Microcirculation. 2019. PMID: 29323451 Free PMC article. Review.
-
Pathogenic roles of autoantibodies in systemic sclerosis: Current understandings in pathogenesis.J Scleroderma Relat Disord. 2020 Jun;5(2):103-129. doi: 10.1177/2397198319870667. Epub 2019 Sep 9. J Scleroderma Relat Disord. 2020. PMID: 35382028 Free PMC article. Review.
References
Publication types
MeSH terms
LinkOut - more resources
Medical