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Randomized Controlled Trial
. 2007 Aug;16(6):1007-17.
doi: 10.1007/s11136-007-9208-2. Epub 2007 May 15.

Responsiveness to change [corrected] due to supportive-expressive group therapy, improvement in mood and disease progression in women with metastatic breast cancer

Julie Lemieux  1 , Dorcas E Beaton, Sheilah Hogg-Johnson, Louise J Bordeleau, Jon Hunter, Pamela J Goodwin
Affiliations
Randomized Controlled Trial

Responsiveness to change [corrected] due to supportive-expressive group therapy, improvement in mood and disease progression in women with metastatic breast cancer

Julie Lemieux et al. Qual Life Res. 2007 Aug.

Erratum in

  • Qual Life Res. 2007 Oct;16(8):1451

Abstract

Objective: To compare the responsiveness of six questionnaires using three hypotheses of change: (i) change due to supportive-expressive group therapy (SEGT), (ii) improved mood defined as a small effect size (.2) on Profile of Mood States (POMS) Total Mood Disturbance score and (iii) progression of disease.

Method: Data from the "Breast Expressive-Supportive Therapy" study, a multicentre randomized controlled trial of change due to SEGT versus standard of care in women with metastatic breast cancer were used. Questionnaires studied were: POMS, Impact of Event Scale, Psychosocial Adjustment to Illness Scale (PAIS), EORTC QLQ-C30, Mental Adjustment to Cancer and a Pain visual analog scale (VAS). Responsiveness to change was evaluated using the standardized response mean. POMS was used as the standard.

Results: POMS was the most responsive questionnaire to change due to SEGT. Questionnaires measuring psychosocial attributes were responsive to improvement in mood. EORTC QLQ-C30, PAIS, PAIN VAS and MAC were the most responsive to disease progression. More responsive questionnaires were associated with the smallest sample size required to detect an effect.

Conclusions: Responsiveness to change is context specific. The POMS was the most responsive questionnaire to psychosocial therapy.

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