Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2007 May 16;2(5):e442.
doi: 10.1371/journal.pone.0000442.

Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic?

Mia T Levine  1 , David J Begun
Affiliations
Comparative Study

Comparative population genetics of the immunity gene, Relish: is adaptive evolution idiosyncratic?

Mia T Levine et al. PLoS One. .

Abstract

The frequency of adaptive evolution acting on common loci in distant lineages remains an outstanding question in evolutionary biology. We asked whether the immunity factor, Relish, a gene with a history of directional selection in Drosophila simulans, shows evidence of a similar selective history in other Drosophila species. We found only weak evidence of recurrent adaptive protein evolution at the Relish locus in three sister species pairs, suggesting that this key component of the insect immune system has an idiosyncratic evolutionary history in Drosophila.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Charlesworth D, Awadalla P. Flowering plant self-incompatibility: the molecular population genetics of Brassica S-loci. Heredity. 1998;81:1–9. - PubMed
    1. Hughes A. Adaptive Evolution of Genes and Genomes. New York: Oxford University Press; 1999. pp. 54–89.
    1. ffrench-Constant RH, Anthony N, Aronstein K, Rocheleau T, Stilwell G. Cyclodiene insecticide resistance: from molecular to population genetics. Ann Rev Ent. 2000;48:447–464. - PubMed
    1. Rees JL. Genetics of hair and skin color. Annu Rev Genet. 2003;37:67–90. - PubMed
    1. Mundy NI, Badcock NS, Hart T, Scribner K, Janssen, et al. Conserved genetic basis of a quantitative plumage trait involved in mate choice. Science. 2004;303:1870–1873. - PubMed

Publication types

LinkOut - more resources