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Case Reports
. 2007 Jun;39(2):145-8.
doi: 10.1016/j.jcv.2007.04.002. Epub 2007 May 16.

Vaccine-associated paralytic poliomyelitis in a patient with MHC class II deficiency

Nima Parvaneh  1 , Shohreh Shahmahmoudi, Hamideh Tabatabai, Mohsen Zahraei, Taha Mousavi, Abdol-Reza Esteghamati, Mohammad M Gooya, Setareh Mamishi, Rakhshandeh Nategh, Olen M Kew
Affiliations
Case Reports

Vaccine-associated paralytic poliomyelitis in a patient with MHC class II deficiency

Nima Parvaneh et al. J Clin Virol. 2007 Jun.

Abstract

Vaccine-associated paralytic poliomyelitis (VAPP) is a rare complication of oral polio vaccine. We describe a fatal case of VAPP in an 8-month-old boy with Major Histocompatibility Class II deficiency. The isolated poliovirus was a Sabin type 2-type 1 recombinant that showed 1.4% VP1 divergence from Sabin type 2.

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