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. 2007 May;8(3):150-62.
doi: 10.1093/bib/bbm018. Epub 2007 May 17.

SenseLab: new developments in disseminating neuroscience information

Chiquito J Crasto  1 , Luis N Marenco, Nian Liu, Thomas M Morse, Kei-Hoi Cheung, Peter C Lai, Gautam Bahl, Peter Masiar, Hugo Y K Lam, Ernest Lim, Huajin Chen, Prakash Nadkarni, Michele Migliore, Perry L Miller, Gordon M Shepherd
Affiliations

SenseLab: new developments in disseminating neuroscience information

Chiquito J Crasto et al. Brief Bioinform. 2007 May.

Abstract

This article presents the latest developments in neuroscience information dissemination through the SenseLab suite of databases: NeuronDB, CellPropDB, ORDB, OdorDB, OdorMapDB, ModelDB and BrainPharm. These databases include information related to: (i) neuronal membrane properties and neuronal models, and (ii) genetics, genomics, proteomics and imaging studies of the olfactory system. We describe here: the new features for each database, the evolution of SenseLab's unifying database architecture and instances of SenseLab database interoperation with other neuroscience online resources.

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Figures

Figure 1
Figure 1
List of neurons and interneurons included in NeuronDB. A similar figure can be found in CellPropDB. The columns in the figure show the region-sub-region-neuron-property hierarchy.
Figure 2
Figure 2
Information presented in NeuronDB. The columns indicate the receptor, current, transmitter properties for the distal apical dendrite (Dad) compartment of the Ca1 Pyramidal Neuron.
Figure 3
Figure 3
Entry in ORDB. Rat ORI7 was one of the first cloned and identified. The figure shows the attributes and values for this OR. Values that appear as links are also stored as attributes. The last attribute in the figure provides a link to an entry in ORMicroarrayDB with links to the results of microarray experiments for this OR.
Figure 4
Figure 4
Results of the multi-attribute search in ORDB. This search feature appears in all SenseLab databases. The end user here wishes to find all taste receptors that have been explored by the laboratory of Dr Linda Buck. The figure also shows partial results in both HTML and XML formats.
Figure 5
Figure 5
A partial list of model Topics in ModelDB.
Figure 6
Figure 6
Entrez-LinkOut broker used for ModelDB. When the link to the PUBMED entry in the upper right hand panel is clicked, it opens the page for the original Hodgkin-Huxley computational model in PUBMED shown in the upper left hand panel. The lower left hand panel displays the LinkOut resources in PUBMED for NDG as a link. When that link is clicked, it results in the Hodgkin-Huxley model link in NDG. The lower right panel shows that the Hodgkin-Huxley model is stored in both ModelDB and the SNNAP database housed at University of Texas Medical School in Houston, Texas. Clicking on the link for ModelDB in NDG then results in the original page illustrated in the upper right hand panel.
Figure 7
Figure 7
BrainPharm ontology diagram.
See this image and copyright information in PMC

References

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