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Randomized Controlled Trial
. 2007 Sep 15;260(1-2):143-6.
doi: 10.1016/j.jns.2007.04.019. Epub 2007 May 23.

Treatment of spinocerebellar ataxia with buspirone

Mitra Assadi  1 , Joseph V Campellone, Christopher G Janson, J Jon Veloski, Robert J Schwartzman, Paola Leone
Affiliations
Randomized Controlled Trial

Treatment of spinocerebellar ataxia with buspirone

Mitra Assadi et al. J Neurol Sci. .

Abstract

Preliminary data suggest potential benefit of 5-HT receptor agonists in the treatment of ataxias. We studied the effects of buspirone in a cohort of twenty patients with spinocerebellar ataxia (SCA). Twenty patients were treated in this double-blind, placebo controlled, cross-over trial with either buspirone HCl 30 mg twice daily or placebo for 3 months. Buspirone was not shown to be superior to placebo in the treatment of patients with SCA.

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  • Buspirone and serotonin in spinocerebellar ataxia.
    Gazulla J, Modrego P. Gazulla J, et al. J Neurol Sci. 2008 May 15;268(1-2):199-200; author reply 200-1. doi: 10.1016/j.jns.2007.12.008. Epub 2008 Jan 28. J Neurol Sci. 2008. PMID: 18222483 No abstract available.

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