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. 2007 Jul;78(5):385-7.
doi: 10.1016/j.fitote.2007.03.010. Epub 2007 Apr 11.

Cytotoxic activity of lignans from Hibiscus cannabinus

Laila Moujir  1 , Ana M L Seca, Artur M S Silva, Manuel R López, Nayely Padilla, José A S Cavaleiro, Carlos P Neto
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Cytotoxic activity of lignans from Hibiscus cannabinus

Laila Moujir et al. Fitoterapia. 2007 Jul.

Abstract

The antimicrobial and cytotoxic activities of six lignans isolated from the core and bark acetone extracts of Hibiscus cannabinus have been investigated. Two compounds (2 and 3) showed strong cytotoxic activity against HeLa, Hep-2 and A-549 cell lines while compound 5 showed moderate activity on HeLa cells when they were in advanced stage of cellular division. The compounds did not exhibit antimicrobial activity.

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