Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2007 Jun;24(6):441.
doi: 10.1136/emj.2006.045104.

Paradoxical embolus illustrating speed of action of recombinant tissue plasminogen activator in massive pulmonary embolism

Affiliations
Case Reports

Paradoxical embolus illustrating speed of action of recombinant tissue plasminogen activator in massive pulmonary embolism

H Madani et al. Emerg Med J. 2007 Jun.

Abstract

A case of a patient who presented with massive pulmonary embolism (PE) requiring thrombolysis with alteplase is reported. The subsequent presence of a patent foramen ovale and paradoxical embolism clinically demonstrated the speed of action of the recombinant tissue plasminogen activator. The advantage of this class of medication when considering the treatment options for a PE in an acute setting is highlighted.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None.

References

    1. Martín F, Sánchez P L, Doherty E.et al Percutaneous transcatheter closure of patent foramen ovale in patients with paradoxical embolism. Circulation 20021061121–1126. - PubMed
    1. Windecker S, Wahl A, Nedeltchev K.et al Comparison of medical treatment with percutaneous closure of patent foramen ovale in patients with cryptogenic stroke. J Am Coll Cardiol 200444750–758. - PubMed
    1. Hugl B, Klein‐Weigel P, Posch L.et al Peripheral ischemia caused by paradoxical embolization: an underestimated problem? Mt Sinai J Med 200572200–206. - PubMed
    1. Capstick T, Henry M T. Efficacy of thrombolytic agents in the treatment of pulmonary embolism. Eur Respir J 200526864–874. - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources