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. 2007 Jun;11(6):706-8.

Pregnancies complicated by multidrug-resistant tuberculosis and HIV co-infection in Durban, South Africa

M Khan  1 , T Pillay, J Moodley, A Ramjee, N Padayatchi
Affiliations
  • PMID: 17519106

Pregnancies complicated by multidrug-resistant tuberculosis and HIV co-infection in Durban, South Africa

M Khan et al. Int J Tuberc Lung Dis. 2007 Jun.

Abstract

Setting: Tertiary hospitals in KwaZulu Natal, South Africa.

Objective: To study the impact of multidrug-resistant tuberculosis (MDR-TB) and human immunodeficiency virus-1 (HIV-1) co-infection during pregnancy on maternal and perinatal outcome.

Design: Prospective study performed between 1996 and 2001. Symptomatic pregnant women were investigated for TB. Those with confirmed MDR-TB were reported on.

Results: Three of five pregnant women with MDR-TB were HIV-1 co-infected. One woman decided to terminate the pregnancy and one experienced pre-term labour. Two neonates had features of growth restriction.

Conclusion: Management of pregnant women with MDR-TB in an HIV-endemic area is possible in developing countries.

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