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Case Reports
. 2007 May;24(5):639-43.
doi: 10.1016/s0761-8425(07)91134-1.

[Acute respiratory distress syndrome complicating Ebstein-Barr virus pneumonia]

[Article in French]
M Riachy  1 , C Baaklini, I Ibrahim, H Azar, C Yaghi, G Dabar, T Bazarbachi, R Nasnas, D Karam-Sarkis, M Germanos, N Maacaron, G Khayat, J Choucair
Affiliations
Case Reports

[Acute respiratory distress syndrome complicating Ebstein-Barr virus pneumonia]

[Article in French]
M Riachy et al. Rev Mal Respir. 2007 May.

Abstract
in English, French

Introduction: In the immuno-competent adult Ebstein-Barr virus (EBV) infection is a self-limiting disease that resolves spontaneously.

Case report: We report a case of acute respiratory distress syndrome (ARDS) complicating severe EBV pneumonia and requiring prolonged artificial ventilation. The diagnosis was confirmed by specific serology and estimation of the viral load by PCR. Apart from supportive treatment with artificial ventilation the medical treatment included the use of Acyclovir and polyclonal immunoglobulins in the early phase and corticosteroids in the late phase. Recovery was progressive and complete.

Conclusion: ARDS can complicate EBV pneumonia in an immuno-competent subject. Its management represents a diagnostic and therapeutic challenge.

Introduction: Chez l’adulte immunocompétent, l’Epstein Barr (EBV) entraîne une maladie autolimitée spontanément résolutive.

Observation: Un syndrome de détresse respiratoire aigu (SDRA) compliquant une pneumonie grave à EBV est rapporté avec le recours à une ventilation artificielle prolongée. Le diagnostic était confirmé par l’usage des sérologies spécifiques et la recherche de la charge d’ADN virale par PCR. À part la stratégie protectrice de la ventilation mécanique, le traitement médical a compris l’utilisation de l’Acyclovir et les immunoglobulines polyclonales dans la phase précoce ainsi que des corticoïdes systémiques dans la phase tardive. La guérison était progressive et complète.

Conclusion: La pneumonie à EBV compliquée d’un SDRA chez les immunocompétents existe. Sa prise en charge est un défi diagnostique et thérapeutique.

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