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Comment
. 2007 Jun 18;96(12):1924-5.
doi: 10.1038/sj.bjc.6603807. Epub 2007 May 22.

Compartmentalisation of EGFR signalling might potentiate the optimal use of EGFR tyrosine kinase inhibitors in cancer therapeutics

M V Karamouzis, P A Konstantinopoulos, A G Papavassiliou
Comment

Compartmentalisation of EGFR signalling might potentiate the optimal use of EGFR tyrosine kinase inhibitors in cancer therapeutics

M V Karamouzis et al. Br J Cancer. .
No abstract available

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References

    1. Barbieri MA, Fernandez-Pol S, Hunker C, Horazdovsky BH, Stahl PD (2004) Role of rab5 in EGF receptor-mediated signal transduction. Eur J Cell Biol 83: 305–314 - PubMed
    1. Ceresa BP, Bahr SJ (2006) Rab7 activity affects epidermal growth factor:epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome. J Biol Chem 281: 1099–1106 - PubMed
    1. Citri A, Yarden Y (2006) EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 7: 505–516 - PubMed
    1. Cullis DN, Phillip B, Baleja JD, Feig LA (2002) Rab11-FIP2, an adaptor protein connecting cellular components involved in internalization and recycling of epidermal growth factor receptors. J Biol Chem 277: 49158–49166 - PubMed
    1. Feng FY, Varambally S, Tomlins SA, Chun PY, Lopez CA, Li X, Davis MA, Chinnaiyan AM, Lawrence TS, Nyati MK (2006) Role of epidermal growth factor receptor degradation in gemcitabine-mediated cytotoxicity. Oncogene 26: 3431–3439 - PubMed