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Comment
. 2007 May;26(5):547-9.
doi: 10.1016/j.immuni.2007.05.003.

T cells doing it for themselves: TGF-beta regulation of Th1 and Th17 cells

Mandy J McGeachy  1 , Daniel J Cua
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T cells doing it for themselves: TGF-beta regulation of Th1 and Th17 cells

Mandy J McGeachy et al. Immunity. 2007 May.
Free article

Abstract

The source of TGF-beta, which regulates inflammation in various disease settings, is unclear. In this issue of Immunity, Li et al. (2007) find that not only does T cell-produced TGF-beta regulate Th1-cell-mediated inflammation, but it is also required for the generation of Th17 cells in vivo.

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