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. 2008 May;62(5):682-5.
doi: 10.1038/sj.ejcn.1602790. Epub 2007 May 16.

Effects of a short-term intervention with a paleolithic diet in healthy volunteers

M Osterdahl  1 , T Kocturk, A Koochek, P E Wändell
Affiliations

Effects of a short-term intervention with a paleolithic diet in healthy volunteers

M Osterdahl et al. Eur J Clin Nutr. 2008 May.

Abstract

Objectives: Prevention of cardiovascular diseases by paleolithic or hunter-gatherer diets has been discussed during recent years.

Methods: Our aim was to assess the effect of a paleolithic diet in a pilot study on healthy volunteers during 3 weeks. The intention was to include 20 subjects, of whom 14 fulfilled the study. Complete dietary assessment was available for six subjects.

Results: Mean weight decreased by 2.3 kg (P<0.001), body mass index by 0.8 (P<0.001), waist circumference by 0.5 cm (P=0.001), systolic blood pressure by 3 mm Hg (P=0.03) and plasminogen activator inhibitor-1 by 72% (P=0.020). Regarding nutrient intake, intake of energy decreased by 36%, and other effects were also observed, both favourable (fat composition, antioxidants, potassium-sodium rate) and unfavourable (calcium).

Conclusion: This short-term intervention showed some favourable effects by the diet, but further studies, including control group, are needed.

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