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. 2007 Jul;28(7):315-20.
doi: 10.1016/j.it.2007.05.001. Epub 2007 May 24.

CD24: a genetic checkpoint in T cell homeostasis and autoimmune diseases

Yang Liu  1 , Pan Zheng
Affiliations

CD24: a genetic checkpoint in T cell homeostasis and autoimmune diseases

Yang Liu et al. Trends Immunol. 2007 Jul.

Abstract

CD24 is widely used as a marker for differentiation of multiple lineages of cells and can provide costimulation for T cells, especially in non-lymphoid target organs. Recent studies demonstrate that CD24 controls an important genetic checkpoint for homeostasis and autoimmune diseases in both mice and humans. Understanding the molecular and cellular basis of CD24 function could provide important insights into T cell biology and autoimmunity.

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