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Review
. 2007 Jun;36(2):239-57, vii.
doi: 10.1016/j.gtc.2007.03.015.

Autoimmune pancreatitis

Alyssa M Krasinskas  1 , Amit Raina, Asif Khalid, Mitchell Tublin, Dhiraj Yadav
Affiliations
Review

Autoimmune pancreatitis

Alyssa M Krasinskas et al. Gastroenterol Clin North Am. 2007 Jun.

Abstract

Autoimmune pancreatitis (AIP) is a benign, IgG4-related, fibroinflammatory form of chronic pancreatitis that can mimic pancreatic ductal adenocarcinoma both clinically and radiographically. Laboratory studies typically demonstrate elevated serum IgG4 levels and imaging studies reveal a diffusely or focally enlarged pancreas with associated diffuse or focal narrowing of the pancreatic duct. The pathologic features include periductal lymphoplasmacytic inflammation, obliterative phlebitis, and abundant IgG4-positive plasma cells. The treatment of choice for AIP is steroid therapy. Diagnostic criteria for AIP have been proposed that incorporate histologic, radiographic, serologic, and clinical information.

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