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Comment
. 2007 Jun 1;129(5):859-61.
doi: 10.1016/j.cell.2007.05.029.

Oriented cell divisions and muscle satellite cell heterogeneity

Giulio Cossu  1 , Shahragim Tajbakhsh
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Free article
Comment

Oriented cell divisions and muscle satellite cell heterogeneity

Giulio Cossu et al. Cell. .
Free article

Abstract

Satellite cells are crucial for maintaining muscle homeostasis and for regeneration following injury. In this issue, Kuang et al. (2007) reveal that muscle satellite cells are a heterogeneous mixture of stem cells and committed myogenic progenitors. They show that asymmetric division of stem cells in the satellite cell niche is a mechanism for generating these two populations.

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