Comment
doi: 10.1016/j.cell.2007.05.029.
Oriented cell divisions and muscle satellite cell heterogeneity
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- PMID: 17540166
- DOI: 10.1016/j.cell.2007.05.029
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Comment
Oriented cell divisions and muscle satellite cell heterogeneity
Cell.
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Abstract
Satellite cells are crucial for maintaining muscle homeostasis and for regeneration following injury. In this issue, Kuang et al. (2007) reveal that muscle satellite cells are a heterogeneous mixture of stem cells and committed myogenic progenitors. They show that asymmetric division of stem cells in the satellite cell niche is a mechanism for generating these two populations.
Comment on
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Asymmetric self-renewal and commitment of satellite stem cells in muscle.Cell. 2007 Jun 1;129(5):999-1010. doi: 10.1016/j.cell.2007.03.044. Cell. 2007. PMID: 17540178 Free PMC article.
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