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Review
. 2007 Aug 3;1159(1-2):63-74.
doi: 10.1016/j.chroma.2007.05.055. Epub 2007 May 18.

Capillary electrophoresis-high resolution sector field inductively coupled plasma mass spectrometry

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Review

Capillary electrophoresis-high resolution sector field inductively coupled plasma mass spectrometry

Jeroen E Sonke et al. J Chromatogr A. .

Abstract

The background and applications of high resolution sector field inductively coupled plasma mass spectrometry (HR-ICP-MS) as a detector for capillary (CE) and gel electrophoretic separations are reviewed. Notable progress has been made in the fields of bioinorganic and environmental (geo-) chemistry. Metallomics, the study of metal species interactions and functions in biological systems, puts substantial technical demands on speciation analysis. The combination of high species resolving power (CE) and high sensitivity-high mass resolving power (HR-ICP-MS) provides a solid base to meet such demands.

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