A methylation rendezvous: reader meets writers
- PMID: 17543855
- DOI: 10.1016/j.devcel.2007.05.011
A methylation rendezvous: reader meets writers
Abstract
It is well established that two marks of silent chromatin, DNA methylation and histone H3 methylation at lysine 9, engage in an epigenetic conversation. In a recent issue of Genes & Development, Smallwood et al. (2007) report that the mammalian HP1 adaptor "translates" methylation information from histone to DNA, helping to cement epigenetic expression states.
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