Follicle-like hemicysts reorganized in monolayer culture of rat thyroid cells in the medium supplemented with isologous serum
- PMID: 1755012
- DOI: 10.1620/tjem.164.223
Follicle-like hemicysts reorganized in monolayer culture of rat thyroid cells in the medium supplemented with isologous serum
Abstract
Monolayer culture of the cells isolated from rat thyroid glands formed a number of large and three-dimensional (about 200-microns diameter) hemicysts in media supplemented with isologous and high-concentration serum. The higher was the concentration of isologous serum, the larger was the hemicysts and the higher was the uptake of 131I of hemicysts. Substitution of heterologous serum, such as calf or fetal calf serum, for the isologous serum failed to form hemicysts.
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