Mutual suppression in the 6 kHz region of sensitive chinchilla cochleae

Abstract

Basilar membrane (BM) vibration was measured using a displacement measuring interferometer for single-tone and two-tone suppression (2TS) paradigms in the 6-9 kHz region of sensitive chinchilla cochleae that had gains near or better than 60 dB. Based on prior studies of basilar membrane vibration, three significant differences remain between BM and auditory nerve (AN) 2TS responses: (1) suppression thresholds in the tail of tuning curves were much higher in BM than the auditory nerve (AN); (2) rates of suppression were significantly higher in AN than BM; and (3) the amplitude of vibration with low-frequency suppressors was always greater than the single-tone displacement rendering it impossible to explain 2TS rate suppression in the AN. The first two differences are eliminated by the results of the present study while the third remains. Suppression amplitudes greater than 40 dB and rates of suppression larger than 2.5 dB/dB were found for low-frequency suppressors. A correlation between both the gain and nonlinearity of the cochlea and 2TS properties indicates that when sensitive cochleae are studied. The third difference between BM and AN behavior could be strictly a function of the high-pass filter characteristic of the inner hair cells.