Systems biology: a switch for sex
- PMID: 17550765
- DOI: 10.1016/j.cub.2007.03.060
Systems biology: a switch for sex
Abstract
The yeast pheromone response pathway works in a graded fashion, such that more pheromone leads to more response, but a recent study has shown that small modifications convert it into a bistable switch, with implications for the evolution and engineering of reaction networks.
Comment on
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Positive-feedback loops as a flexible biological module.Curr Biol. 2007 Apr 17;17(8):668-77. doi: 10.1016/j.cub.2007.03.016. Epub 2007 Mar 29. Curr Biol. 2007. PMID: 17398098 Free PMC article.
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