Spontaneous bacterial peritonitis
- PMID: 17551068
- PMCID: PMC2600063
- DOI: 10.1136/pgmj.2006.056168
Spontaneous bacterial peritonitis
Abstract
Spontaneous bacterial peritonitis (SBP) is the infection of ascitic fluid in the absence of any intra-abdominal, surgically treatable source of infection. Despite timely diagnosis and treatment its reported incidence in ascitic patients varies between 7-30%. Ascitic paracentesis remains the chief diagnostic procedure. Automated cell counters have the same diagnostic accuracy as the manual measurement of white cells. Lately, the use of leucocyte reagent strips (dipsticks) has emerged as a useful alternative. Examination of the fluid is not complete unless the sample is inoculated in blood culture bottles. Treatment is currently with third-generation cephalosporins or oral quinolones. Following a single episode of SBP patients should have long term antibiotic prophylaxis.
Conflict of interest statement
Conflict of interest: none stated
References
-
- Conn H O, Fessel J M. Spontaneous bacterial peritonitis in cirrhosis: variations on a theme. Medicine 197150161–197. - PubMed
-
- Guarner C, Soriano G. Spontaneous bacterial peritonitis. Semin Liver Dis 199717203–217. - PubMed
-
- Runyon B A. Management of adult patients with ascites due to cirrhosis – AASLD Practice Guideline. Hepatology 2004391–16. - PubMed
-
- Runyon B A. Ascites and spontaneous bacterial peritonitis. In: Feldman M, Friedman LS, Sleisenger MH, eds. Sleisenger and Fordran's gastrointestinal and liver disease, 8th ed. Philadelphia: Saunders, 20061935–1964.
