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. 2007 Jun 21;5(12):1845-8.
doi: 10.1039/b705805e. Epub 2007 May 16.

Oligodeoxynucleotides incorporating structurally simple 5-alkynyl-2'-deoxyuridines fluorometrically respond to hybridization

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Oligodeoxynucleotides incorporating structurally simple 5-alkynyl-2'-deoxyuridines fluorometrically respond to hybridization

Robert H E Hudson et al. Org Biomol Chem. .

Abstract

Selected 5-ethynyl derivatives of 2'-deoxyuridine are shown to fluorometrically respond to hybridization and selectively base-pair to adenine whilst maintaining duplex stability.

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