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. 2007 Jul;35(Web Server issue):W354-6.
doi: 10.1093/nar/gkm390. Epub 2007 Jun 6.

DOMAC: an accurate, hybrid protein domain prediction server

Jianlin Cheng  1
Affiliations

DOMAC: an accurate, hybrid protein domain prediction server

Jianlin Cheng. Nucleic Acids Res. 2007 Jul.

Abstract

Protein domain prediction is important for protein structure prediction, structure determination, function annotation, mutagenesis analysis and protein engineering. Here we describe an accurate protein domain prediction server (DOMAC) combining both template-based and ab initio methods. The preliminary version of the server was ranked among the top domain prediction servers in the seventh edition of Critical Assessment of Techniques for Protein Structure Prediction (CASP7), 2006. DOMAC server and datasets are available at: http://www.bioinfotool.org/domac.html.

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Figures

Figure 1.
Figure 1.
Domain prediction result of CASP7 target T0324. The protein is predicted to have two domains. Domain 1 has two non-continuous segments, spanning from residues 1 to 16 and residues 82 to 208, respectively. Domain 2 spans from residues 17 to 81. The templates used to make the domain prediction are identified by PDB code + chain id. The chain in a single-chain protein is always assigned chain id ‘A’ instead of ‘-’.
See this image and copyright information in PMC

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