Adiponectin and renal disease progression: another epidemiologic conundrum?
- PMID: 17554349
- DOI: 10.1038/sj.ki.5002319
Adiponectin and renal disease progression: another epidemiologic conundrum?
Abstract
In an analysis based on the Mild to Moderate Kidney Disease (MMKD) study, adiponectin, a pleiotropic, insulin-sensitizing, anti-inflammatory and vasculo-protective cytokine, was directly related to renal disease progression. The precise definition of this apparently paradoxical association now requires that the research focus be moved from the study database to the experimental laboratory.
Comment on
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Gender-specific association of adiponectin as a predictor of progression of chronic kidney disease: the Mild to Moderate Kidney Disease Study.Kidney Int. 2007 Jun;71(12):1279-86. doi: 10.1038/sj.ki.5002191. Epub 2007 Apr 25. Kidney Int. 2007. PMID: 17457380
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