Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008;115(4):567-73.
doi: 10.1007/s00702-007-0758-9. Epub 2007 Jun 8.

Future aspects of botulinum neurotoxins

K R Aoki  1
Affiliations
Review

Future aspects of botulinum neurotoxins

K R Aoki. J Neural Transm (Vienna). 2008.

Abstract

The future of botulinum neurotoxin (BoNT) development is expected to proceed along two lines: the development of novel indications and the development of novel products. New indications will likely be based on the neuromuscular mode of action of BoNTs, as well as action on primary sensory fibers and other neuronal types. Novel BoNT products may be designed for increased specificity or enhanced duration. As new products enter the market, it will be important for each to demonstrate efficacy and safety. Unfortunately, the future of BoNTs will also likely include attempts to obtain and distribute unlicensed and illegal BoNT products that may pose substantial risks to patients.

PubMed Disclaimer

References

    1. Curr Med Res Opin. 2005 Mar;21(3):433-8 - PubMed
    1. Ophthalmologica. 2002 Jan-Feb;216(1):50-4 - PubMed
    1. Am J Physiol Heart Circ Physiol. 2002 Dec;283(6):H2627-35 - PubMed
    1. Nat Neurosci. 2002 Sep;5(9):856-60 - PubMed
    1. Mov Disord. 2004 Mar;19 Suppl 8:S42-7 - PubMed

LinkOut - more resources