IK1 and cardiac hypoxia: after the long and short QT syndromes, what else can go wrong with the inward rectifier K+ currents?
- PMID: 17561108
- PMCID: PMC3745007
- DOI: 10.1016/j.yjmcc.2007.04.015
IK1 and cardiac hypoxia: after the long and short QT syndromes, what else can go wrong with the inward rectifier K+ currents?
Comment on
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Cardiac IK1 underlies early action potential shortening during hypoxia in the mouse heart.J Mol Cell Cardiol. 2007 Jul;43(1):27-38. doi: 10.1016/j.yjmcc.2007.04.002. Epub 2007 Apr 10. J Mol Cell Cardiol. 2007. PMID: 17498734 Free PMC article.
References
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- Hutter OF, Noble D. Rectifying properties of heart muscle. Nature. 1960;188:495. - PubMed
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- Nichols CG, Lopatin AN. Inward rectifier potassium channels. Annu Rev Physiol. 1997;59:171–91. - PubMed
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- Zaritsky JJ, Eckman DM, Wellman GC, Nelson MT, Schwarz TL. Targeted disruption of Kir2.1 and Kir2.2 genes reveals the essential role of the inwardly rectifying K+ current in K+-mediated vasodilation. Circ Res. 2000;87:160–6. - PubMed
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