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Case Reports
. 2007 Apr 15;3(3):313-5.

A patient with sickle cell disease and a low baseline sleeping oxygen saturation

Mary H Wagner  1 , Richard B Berry
Affiliations
Case Reports

A patient with sickle cell disease and a low baseline sleeping oxygen saturation

Mary H Wagner et al. J Clin Sleep Med. .
No abstract available

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Figures

Figure 1
Figure 1
A 30-second tracing is shown during non-rapid eye movement sleep. The ventilation appears normal, but the pulse oximetry (SpO2) value is reduced. ROC refers to right outer canthus electrooculogram; LOC, left outer canthus electrooculogram; EMG, electromyogram; EKG, electrocardiogram.
Figure 2
Figure 2
A: Hemoglobin extinction curves for RHb, O2Hb, and COHb at different wave lengths of light. Note that the y axis is a log scale. B: Empirical curve of the ratio of absorption of radiation at wavelengths of 660 and 940 nm. The AC is the pulse added absorption and DC the steady state or background absorbance. (Adapted from Temper KK, Barker SJ. Pulse Oximetry. Anesthesiology 1989;70:98–108).
Figure 3
Figure 3
The oxygen hemoglobin dissociation curve showing the values for hemoglobin (Hb) A (solid line) and a patient with Hb S (dashed line). For the patient with Hb S, the P50 is 38 mm Hg, and an SaO2 value of 92% corresponds to a PO2 of 90 mm Hg.
See this image and copyright information in PMC

References

    1. Temper KK, Barker SJ. Pulse Oximetry. Anesthesiology. 1989;70:98–108. - PubMed
    1. Blaisdell Carol J. Sickle cell disease and breathing during sleep. In: Loughlin GM, Carroll JL, Marcus C, editors. Sleep and Breathing in Children. A Developmental Approach. New York: Marcel Dekker, Inc; 2000. pp. 755–63.
    1. Seakins M, Gibbs WN, Milner PF, et al. Erthyrocyte Hb-S concentration—an important factor in low oxygen affinity of blood in sickle cell anemia. J Clin Invest. 1973;52:422–32. - PMC - PubMed
    1. Craft JA, Alessandrini E, Kenney LB, et al. Comparison of oxygenation measurements in pediatric patients during sickle cell crises. J Pediatr. 1994;24:93–5. - PubMed
    1. Ortiz FO, Aldrich TK, Nagel RL, Benjamin LJ. Accuracy of pulse oximetry in sickle disease. Am J Respir Crit Care Med. 1999;169:447–51. - PubMed

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