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. 2007 Jul;37(7):615-22.
doi: 10.1007/s00247-007-0467-4. Epub 2007 May 22.

PET-CT in pediatric Langerhans cell histiocytosis

Sue C Kaste  1 , Carlos Rodriguez-Galindo, Mary E McCarville, Barry L Shulkin
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PET-CT in pediatric Langerhans cell histiocytosis

Sue C Kaste et al. Pediatr Radiol. 2007 Jul.

Abstract

Our objective was to assess the utility of PET-CT in five pediatric patients with Langerhans cell histiocytosis (LCH) who underwent PET-CT imaging for clinical staging and determination of lesion activity at various stages of treatment and follow-up. PET-CT combines the anatomic detail of CT and the physiologic activity of (18)F-FDG imaging. We conclude that PET-CT information is clinically useful to evaluate disease activity and response to therapy and provides information that cannot be obtained from technetium 99m methylene diphosphonate bone scans or radiographs.

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